308 research outputs found

    Urban Ecosystem Services and Tourism

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    Urban tourism depends on the place specific qualities of destinations. In many cities, climate change poses a threat to these qualities, through increasing risk of excessive heat, draught and flooding. Cities need to adapt to reduce these risks. One way of doing this is to improve their green infrastructure. Urban forests, parks, rivers and wetlands may help reduce the effects of climate change in cities. At the same time, green infrastructure provide a variety of ecosystem services to the community. In particular, cultural ecosystem services such as recreation, andesthetical values take place in urban green infrastructure; they provide value in the form of improved experiences. These mainly benefit the locals but they may also be important for tourism. Such relations between ecosystem services and tourism have in earlier literature been recognized in rural contexts but very seldom in urban. This paper reports preliminary findings from qualitative case studies in the South of Sweden and Berlin, Germany. They focus on how urban planning projects (primarily aimed at mitigating GHG emissions and adapting to climatechange) can be extended to develop places where experience values for both residents and visitors are created alongside other kinds of ecosystem services. We suggest that the need for climate change adaptation in a city may be used as a means to improve its place specific qualities as a tourist destination. By developing green infrastructure in innovative and environmentally friendly ways, the quality of ecosystem services improves, including those relevant for both visitors and residents. Protecting and building green infrastructure, therebyenhancing a city´s visible qualities and its reputation as a sustainable destination, may also be valuable in marketing the city

    Polymonad programming in Haskell

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    Polymonads were recently introduced by Hicks et al. as a unified approach to programming with different notions of monads. Their work was mainly focussed on foundational aspects of the approach. In this article, we show how to incorporate the notion of polymonads into Haskell, which is the first time this has been done in a full-scale language. In particular, we show how polymonads can be represented in Haskell, give a justification of the representation through proofs in Agda, and provide a plugin for the Glasgow Haskell Compiler (GHC) that enables their use in practice. Finally, we demonstrate the utility of our system by means of examples concerned with session types and the parameterized effect monad. This work provides a common representation of a number of existing approaches to generalized monads in Haskell

    Polymonad programming in Haskell

    Get PDF
    Polymonads were recently introduced by Hicks et al. as a unified approach to programming with different notions of monads. Their work was mainly focussed on foundational aspects of the approach. In this article, we show how to incorporate the notion of polymonads into Haskell, which is the first time this has been done in a full-scale language. In particular, we show how polymonads can be represented in Haskell, give a justification of the representation through proofs in Agda, and provide a plugin for the Glasgow Haskell Compiler (GHC) that enables their use in practice. Finally, we demonstrate the utility of our system by means of examples concerned with session types and the parameterized effect monad. This work provides a common representation of a number of existing approaches to generalized monads in Haskell

    Developing urban tourism in green infrastructure

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    Urban tourism depends on the place specific qualities of destinations. In many cities, climate change poses a threat to these qualities, through increasing risk of excessive heat, draught and flooding. Cities need to adapt to reduce these risks. One way of doing this is to improve their green infrastructure. Urban forests, parks, rivers and wetlands may help reduce the effects of climate change in cities. At the same time, green infrastructure provide a variety of ecosystem services to the community. In particular, cultural ecosystem services such as recreation, and esthetical values take place in urban green infrastructure; they provide value in the form of improved experiences. These mainly benefit the locals but they may also be important for tourism. Such relations between ecosystem services and tourism have in earlier literature been recognized in rural contexts but very seldom in urban.This paper reports preliminary findings from qualitative case studies in Malmö, Lund, and Helsingborg in the South of Sweden. They focus on how urban planning projects (primarily aimed at mitigating GHG emissions and adapting to climate change) can be extended to develop places where experience values for both residents and visitors are created alongside other kinds of ecosystem services.We suggest that the need for climate change adaptation in a city may be used as a means to improve its place specific qualities as a tourist destination. By developing green infrastructure in innovative and environmentally friendly ways, the quality of ecosystem services improves, including those relevant for both visitors and residents. Protecting and building green infrastructure, thereby enhancing a city´s visible qualities and its reputation as a sustainable destination, may also be valuable in marketing the city

    Organochemical Characterization of Peat Reveals Decomposition of Specific Hemicellulose Structures as the Main Cause of Organic Matter Loss in the Acrotelm

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    Peatlands store carbon in the form of dead organic residues. Climate change and human impact impose risks on the sustainability of the peatlands carbon balance due to increased peat decomposition. Here, we investigated molecular changes in the upper peat layers (0-40 cm), inferred from high-resolution vertical depth profiles, from a boreal peatland using two-dimensional H-1-C-13 nuclear magnetic resonance (NMR) spectroscopy, and comparison to delta C-13, delta N-15, and carbon and nitrogen content. Effects of hydrological conditions were investigated at respective sites: natural moist, drainage ditch, and natural dry. The molecular characterization revealed preferential degradation of specific side-chain linkages of xylan-type hemicelluloses within 0-14 cm at all sites, indicating organic matter losses up to 25%. In contrast, the xylan backbone, galactomannan-type hemicelluloses, and cellulose were more resistant to degradation and accumulated at the natural moist and drainage site. delta C-13, delta N-15, and carbon and nitrogen content did not correlate with specific hemicellulose structures but reflected changes in total carbohydrates. Our analysis provides novel insights into peat carbohydrate decomposition and indicates substantial organic matter losses in the acrotelm due to the degradation of specific hemicellulose structures. This suggests that variations in hemicellulose content and structure influence peat stability, which may have important implications with respect to climate change

    A Possible Mechanism behind Autoimmune Disorders Discovered By Genome-Wide Linkage and Association Analysis in Celiac Disease

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    Celiac disease is a common autoimmune disorder characterized by an intestinal inflammation triggered by gluten, a storage protein found in wheat, rye and barley. Similar to other autoimmune diseases such as type 1 diabetes, psoriasis and rheumatoid arthritis, celiac disease is the result of an immune response to self-antigens leading to tissue destruction and production of autoantibodies. Common diseases like celiac disease have a complex pattern of inheritance with inputs from both environmental as well as additive and non-additive genetic factors. In the past few years, Genome Wide Association Studies (GWAS) have been successful in finding genetic risk variants behind many common diseases and traits. To complement and add to the previous findings, we performed a GWAS including 206 trios from 97 nuclear Swedish and Norwegian families affected with celiac disease. By stratifying for HLA-DQ, we identified a new genome-wide significant risk locus covering the DUSP10 gene. To further investigate the associations from the GWAS we performed pathway analyses and two-locus interaction analyses. These analyses showed an over-representation of genes involved in type 2 diabetes and identified a set of candidate mechanisms and genes of which some were selected for mRNA expression analysis using small intestinal biopsies from 98 patients. Several genes were expressed differently in the small intestinal mucosa from patients with celiac autoimmunity compared to intestinal mucosa from control patients. From top-scoring regions we identified susceptibility genes in several categories: 1) polarity and epithelial cell functionality; 2) intestinal smooth muscle; 3) growth and energy homeostasis, including proline and glutamine metabolism; and finally 4) innate and adaptive immune system. These genes and pathways, including specific functions of DUSP10, together reveal a new potential biological mechanism that could influence the genesis of celiac disease, and possibly also other chronic disorders with an inflammatory component

    A transcriptional timetable of autumn senescence

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    BACKGROUND: We have developed genomic tools to allow the genus Populus (aspens and cottonwoods) to be exploited as a full-featured model for investigating fundamental aspects of tree biology. We have undertaken large-scale expressed sequence tag (EST) sequencing programs and created Populus microarrays with significant gene coverage. One of the important aspects of plant biology that cannot be studied in annual plants is the gene activity involved in the induction of autumn leaf senescence. RESULTS: On the basis of 36,354 Populus ESTs, obtained from seven cDNA libraries, we have created a DNA microarray consisting of 13,490 clones, spotted in duplicate. Of these clones, 12,376 (92%) were confirmed by resequencing and all sequences were annotated and functionally classified. Here we have used the microarray to study transcript abundance in leaves of a free-growing aspen tree (Populus tremula) in northern Sweden during natural autumn senescence. Of the 13,490 spotted clones, 3,792 represented genes with significant expression in all leaf samples from the seven studied dates. CONCLUSIONS: We observed a major shift in gene expression, coinciding with massive chlorophyll degradation, that reflected a shift from photosynthetic competence to energy generation by mitochondrial respiration, oxidation of fatty acids and nutrient mobilization. Autumn senescence had much in common with senescence in annual plants; for example many proteases were induced. We also found evidence for increased transcriptional activity before the appearance of visible signs of senescence, presumably preparing the leaf for degradation of its components

    Prevalence of osteoporosis and incidence of hip fracture in women - secular trends over 30 years

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    <p>Abstract</p> <p>Background</p> <p>The number of hip fractures during recent decades has been reported to be increasing, partly because of an increasing proportion of elderly women in the society. However, whether changes in hip fracture annual incidence in women are attributable to secular changes in the prevalence of osteoporosis is unclear.</p> <p>Methods</p> <p>Bone mineral density was evaluated by single-photon absorptiometry at the distal radius in 456 women aged 50 years or above and living in the same city. The measurements were obtained by the same densitometer during three separate time periods: 1970-74 (n = 106), 1987-93 (n = 175) and 1998-1999 (n = 178), and the age-adjusted prevalence of osteoporosis in these three cohorts was calculated. Additionally, all hip fractures sustained in the target population of women aged 50 years or above between 1967 and 2001 were registered, whereupon the crude and the age-adjusted annual incidence of hip fractures were calculated.</p> <p>Results</p> <p>There was no significant difference in the age-adjusted prevalence of osteoporosis when the three cohorts were compared (P = 1.00). The crude annual incidence (per 10,000 women) of hip fracture in the target population increased by 110% from 40 in 1967 to 84 in 2001. The overall trend in the crude incidence between 1967 and 2001 was increasing (1.58 per 10,000 women per year; 95 percent confidence interval, 1.17 to 1.99), whereas the age-adjusted incidence was stable over the same period (0.22 per 10,000 women per year; 95 percent confidence interval, -0.16 to 0.60).</p> <p>Conclusions</p> <p>The increased number of hip fracture in elderly women is more likely to be attributable to demographic changes in the population than to secular increase in the prevalence of osteoporosis.</p
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